Clinical Lab Associate 1 - Histology, 3rd Shift

Personalis

Personalis

Fremont, CA, USA
USD 28-31 / hour + Equity
Posted on Jan 24, 2026

At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care throughout the patient journey. Our highly sensitive assays combine tumor-and-normal profiling with proprietary algorithms to deliver advanced insights even as cancer evolves over time. Our products are designed to detect minimal residual disease (MRD) and recurrence at the earliest timepoints, enable selection of targeted therapies based on ultra-comprehensive genomic profiling, and enhance biomarker strategy for drug development. Personalis is based in Fremont, California.

Shift Details: Monday - Friday, 8:00pm - 4:30am

Responsibilities:

Participates in a hands-on fashion to the daily lab activities in one of the following areas by performing and assisting in laboratory tests and processes according to the laboratory’s standard operating procedures:

  • Main responsibilities are to support the Histopathology Team: Prepare FFPE samples for microscopic evaluation by a pathologist- microtomy, H&E staining, and coverslipping of slides. Perform instrument maintenance and operation. Digital slide image generation, image quality control and transfer to pathology team.
  • Other responsibilities may include supporting the Extractions Team: Extract DNA and RNA from different sample types (fixed tissues, frozen tissue, blood, saliva and more). Perform quality control of samples and sample storage and management. Perform data transfer to the Library Prep Team.

Additional Responsibilities:

  • Escalates issues to a supervisor/ lab manager when problems arise with sample processing
  • Procures appropriate supplies and equipment to maximize department efficiency and meet established budgetary and quality goals
  • Supports and ensures compliance with all department and company policies and procedures.
  • Document all corrective actions taken when test systems deviate from the laboratory’s established performance specifications.
  • Performs other duties as assigned.

Education and Experience:

  • BA/BS in a biological discipline
  • 0-2+ years of relevant laboratory experience as a laboratory technician, experience with histology lab equipment is a plus
  • Excellent organization and communication skills
  • Strong desire to work in a demanding, high-energy, hands-on environment
  • Ability to work within a team
  • Physical demands include stooping, turning, bending, squatting, kneeling, and the ability to lift up to 25 lbs.

The hiring range for this position is $28 to $31 per hour, which may factor in various geographic regions. This shift is eligible for a shift differential pay bonus. The base pay actually offered will take into account internal equity and also may vary depending on the candidate’s geographic region, job-related knowledge, skills, and experience among other factors. Our full-time regular positions also include an annual performance-based bonus (or a sales incentive plan) and long-term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, dependent on the level and position offered.

Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals. As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations. If you need an accommodation to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please let your recruiter know, if/when they contacts you.

Protecting Our Candidates: At Personalis, we value your security. Please note that all official correspondence from our team will come exclusively from @personalis.com email addresses. We will never ask for personal financial information or conduct interviews over text or chat platforms. If you receive a suspicious request, it is likely a scam. We are committed to a safe recruitment experience and actively work with authorities to investigate and prosecute cyber crimes targeting our community.

Personalis is an Equal Opportunity Employer/Minorities/Females/Veterans/Disabilities. Personalis offers a competitive compensation package and benefits including medical, dental, vision, 401(k) match, ESPP, tuition reimbursement, sick/vacation time, commuter benefits/ EV charging stations, onsite gym, and wellness benefits. (For US only, benefits in other countries may vary.)

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