SENIOR DIRECTOR, HEAD OF PROGRAM MANAGEMENT

At Day One, we are focused on advancing first- or best-in-class medicines for childhood and adult diseases with equal intensity. We were founded to address the lack of new therapies resulting from the traditional drug development model, that has left children with cancer and their families waiting too long for new, life-changing treatments. Our aim is to accelerate better, targeted treatments so patients of any age can look forward from ‘day one’ to the future they’ve envisioned.

POSITION SUMMARY:

The Senior Director, Head of Program Management (PM), will be responsible for establishing and leading a first-class Program Management Organization (PMO) in support of the Day One portfolio, from late preclinical through commercial stage, inclusive of CMC activities. This individual will also directly support the Ojemda program as a key member of the Ojemda Product Team, being a key strategic and operational partner to the Product Team Leader (PTL) to ensure timely execution of all product activities on budget, particularly those on the critical path to delivery of key program and corporate milestones. This position will report to the Head of R&D.

Strong preference for candidates in the San Francisco Bay Area or Greater Boston area who can work a hybrid schedule with regular in-office days.

ESSENTIAL DUTIES AND RESPONSIBILITIES:

• Define the mission, operating model, tools and best PM practices across the R&D portfolio
• Lead through example by providing world class PM support to our flagship program, Ojemda
• Be a strategic and operational partner to the Ojemda PTL in all aspects of program planning and execution
• Develop and implement standardized project management frameworks (e.g. tools, processes, and behaviors) for programs from early to late development and through commercialization, such as risk management, communication plans, stage-gates and budget tracking
• Drive cross-functional alignment and operational excellence of all product teams. Critical cross-functional stakeholders are anticipated to include, for example:
  • Chief of Staff to the Chief Executive Officer
  • Corporate Finance (especially FP&A)
  • Head, Strategy and Operations within Research and Development
  • Chief Technical Officer (Head of CMC)
  • Head of Development Operations
• Partner with Finance to align on budget planning, forecasting and resource allocation across the portfolio
• Partner with CMC to incorporate CMC deliverables into the product plan, developing scenarios and risk assessments as required
• Provide strategic leadership to the PMO and product teams to meet corporate objectives
• Identify and mitigate product and portfolio risks proactively, anticipating issues and implementing contingency strategies to ensure timelines and budgets are met
• Lead and mentor a growing team of program managers, fostering a culture of accountability, collaboration and continuous professional development
• Continuously assess and optimize project management tools and systems, incorporating lessons learned and evolving company needs
• Serve as a thought partner to senior leadership on program operational strategy, scenario planning and portfolio trade-offs

On a by-program basis:

• Ensure the creation and maintenance of project/program(s) timelines and interdependencies within each product team, as well as appropriate stage-gates for investment
• Provide project coordination and communication in support of cross-functional product team(s) and all subteams
• Establish and maintain metrics to track projects and provide real-time reporting of project status
• Identify issues and risks and work with the team to develop mitigation strategies
• Coordinate and lead all aspects of internal product team meetings, including agenda drafting and documentation of key discussion points, decisions, and action items
• As the program advances, work with key stakeholders to ensure project management work for regulatory submissions such as INDs and global NDA/BLA/MAA of
• assets in partnership with regulatory operations

QUALIFICATIONS

• Bachelor’s degree in Life Sciences or relevant field
• Advanced degree (MS, PhD, PharmD or MBA, or equivalents) strongly preferred
• Project management certification (e.g., PMP or equivalent) is highly desirable
• 12+ years of relevant experience in (bio)pharma program management and/or related life sciences companies
• Experience across multiple stages of research and clinical development required with exposure to commercial and life cycle management highly desired
• Proven track record managing large, complex, global and cross-functional programs with significant budget and timelines to drive successful execution on program strategy
• Experience working in a small or mid-size biotech highly desirable
• Proven track record of managing other program managers and ability to build and scale teams
• Experience managing external collaborations, vendors, CROs and partnerships is a plus
• Superior written, verbal communication, organizational and people skills
• Ability to translate high-level goals and strategies into executable plans
• Strong data analysis and reporting skills highly desirable
• Ability to communicate and drive adoption of new processes, systems and ways of working
• Strong capabilities with contemporary project management tools (e.g., MS Project, Smartsheet, etc)

The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification.

INTERVIEW INTEGRITY

At Day One, we expect each candidate to engage authentically, representing their true qualifications and experiences. As part of our screening process, we will conduct several interviews and background verification. This ensures candidates have the skills they claim and align with our values. We are excited to learn more about you and to create a genuine experience for everyone.

COMPENSATION AND BENEFITS

The salary range for this position is $250,000 - $275,000. Day One considers a range of factors when determining base compensation. These considerations mean actual compensation will vary.

Please visit https://www.dayonebio.com/benefits to see our competitive benefits.

DISCLAIMER

Day One Biopharmaceuticals is committed to providing an environment of mutual respect where equal employment opportunities are available to all applicants without regard to race, color, religion, sex, pregnancy (including childbirth and related medical conditions), national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information (including characteristics and testing), military and veteran status, and any other characteristic protected by applicable law.

We are unable to sponsor or take over sponsorship of any applicant work visas at this time.

Recruitment & Staffing Agencies: Day One Biopharmaceuticals does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Day One Biopharmaceuticals or its employees is strictly prohibited unless contacted directly by Day One Biopharmaceutical’s internal HR team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Day One Biopharmaceuticals, and Day One Biopharmaceuticals will not owe any referral or other fees with respect thereto.